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Ro 23-7553

Ro 23-7553 is a mitochondrial inhibitor. Ro 23-7553 promotes chondrocyte differentiation at physiological concentrations, while supraphysiological concentrations inhibit both proliferation and differentiation. Ro 23-7553 can be used for the study of cancer[1].

Product Specifications

CAS Number

[118694-43-2]

UNSPSC

12352211

Target

Mitochondrial Metabolism

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

C[C@@]12[C@](CC=C2[C@H](C)CC#CC(C)(O)C)([H])/C(CCC1)=C/C=C3C([C@H](C[C@@H](C\3)O)O)=C

Molecular Formula

C27H38O3

Molecular Weight

410.59

References & Citations

[1]Farquharson C, et al. In vivo and in vitro effect of 1,25-dihydroxyvitamin D3 and 1,25-dihydroxy-16-ene-23-yne-vitamin D3 on the proliferation and differentiation of avian chondrocytes: their role in tibial dyschondroplasia. J Endocrinol. 1996 Mar;148 (3) :465-74.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 1

Curated Selection

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