IO-21
IO-21 (Compound 3) is a candidate cytoprotective agent. IO-21 exhibits a marked cytoprotective effect. IO-21 shows a potent inhibitory activity against HCl•ethanol-induced lesions. IO-21 shows a MIC of 50 μg/mL against Helicobacter pylori 7795. IO-21 can be used in the research of gastric mucosal ulcers[1].
Product Specifications
CAS Number
[114833-91-9]
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
C1(N2C=CC=N2)=NC=NC(N3C=CC=N3)=C1
Molecular Formula
C10H8N6
Molecular Weight
212.21
References & Citations
[1]Ikeda M, et al. Cytoprotective effects of 4,6-bis (1H-pyrazol-1-yl) pyrimidine and related compounds on HCI.ethanol-induced gastric lesions in rats. Chem Pharm Bull (Tokyo) . 1997 Mar;45 (3) :549-51.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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