Tiqueside

Tiqueside (CP‐88,818) is an orally active cholesterol absorption inhibitor. Tiqueside inhibits absorption of both dietary cholesterol and endogenous cholesterol excreted into the intestinal lumen via the bile. Tiqueside can be used in the research of hypercholesterolemia[1].

Product Specifications

CAS Number

[99759-19-0]

Product Name Alternative

CP‐88,818; β‐Tigogenin cellobioside

UNSPSC

12352005

Target

CETP

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Smiles

C[C@@H]1[C@@]2(CC[C@@H](C)CO2)O[C@]3([H])[C@@]1([H])[C@@]4([C@@]([C@@]5([H])[C@]([C@@]6([C@@](C[C@@H](O[C@]7([H])O[C@@H]([C@@H](O[C@]8([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]8O)CO)[C@H](O)[C@H]7O)CO)CC6)([H])CC5)C)([H])CC4)([H])C3)C

Molecular Formula

C39H64O13

Molecular Weight

740.92

References & Citations

[1]Harwood HJ Jr, et al. Pharmacologic consequences of cholesterol absorption inhibition: alteration in cholesterol metabolism and reduction in plasma cholesterol concentration induced by the synthetic saponin beta-tigogenin cellobioside (CP-88818; tiqueside) . J Lipid Res. 1993 Mar;34 (3) :377-95.