Pibrozelesin (hydrobromide)
Pibrozelesin hydrobromide is a hydrolytic prodrug of Carzelesin (HY-19601) . Pibrozelesin hydrobromide has an anticancer activity. Carzelesin is a cyclopropylpyrroloindole precursor molecule and effectively inhibits tumor growth. Carzelesin may be used in cancer research[1].
Product Specifications
CAS Number
[148778-32-9]
UNSPSC
12352005
Target
Drug Intermediate
Related Pathways
Others
Field of Research
Cancer
Smiles
O=C(C(C1=C(C(CN2C(C3=CC4=C(N3)C(OC)=C(OC)C(OC)=C4)=O)CBr)C2=C5)=C(C)NC1=C5OC(N6CCN(CC6)C)=O)OC.Br
Molecular Formula
C32H37Br2N5O8
Molecular Weight
779.47
References & Citations
[1]Felber JG, et al. 40 Years of Duocarmycins: A Graphical Structure/Function Review of Their Chemical Evolution, from SAR to Prodrugs and ADCs. JACS Au. 2022 Nov 15;2 (12) :2636-2644.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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