T 588
T 588 is an orally active neuroprotective agent. T 588 can increase acetylcholine release from the frontal cortex and hippocampus and meliorate cognitive dysfunction. T 588 can protect cerebellar granule cells from glutamate neurotoxicity. T 588can be used for the research of neurological disease, such as Alzheimer's disease[1].
Product Specifications
CAS Number
[142935-03-3]
UNSPSC
12352005
Target
NAChR
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
CCN(CC)CCOC[C@@H](C1=CC=C(SC=C2)C2=C1)O.Cl
Molecular Formula
C16H24ClNO2S
Molecular Weight
329.89
References & Citations
[1]Ikeda K, et al. T-588, a novel neuroprotective agent, delays progression of neuromuscular dysfunction in wobbler mouse motoneuron disease. Brain Res. 2000 Mar 6;858 (1) :84-91.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Curated Selection
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