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MK-8718

MK-8718 is a potent and orally active HIV protease inhibitor containing a morpholine aspartate binding group. MK-8718 can be used for the research of infection[1].

Product Specifications

CAS Number

[1582729-24-5]

UNSPSC

12352005

Target

HIV Protease

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Smiles

O=C(OC[C@H]1NC[C@@H](CCC2=C(NC([C@@H](N)[C@@H](C3=CC=C(Cl)C=C3)C4=CC(F)=CC(F)=C4)=O)C=NC=C2F)OC1)NCC(F)(F)F

Molecular Formula

C30H30ClF6N5O4

Molecular Weight

674.03

References & Citations

[1]Bungard CJ, et al. Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group. ACS Med Chem Lett. 2016 May 9;7 (7) :702-7.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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