EXP-6803
EXP-6803 is a specific nonpeptide angiotensin II receptor antagonist with antihypertensive activity. EXP-6803 inhibits the contractile response to angiotensin II with a pA2 value of 7.20. EXP-6803 effectively blocks responses to angiotensin I and II while not affecting responses to bradykinin or acetylcholine in guinea pig ileum. EXP-6803 can be used for hypertension research[1].
Product Specifications
CAS Number
[114773-44-3]
UNSPSC
12352005
Target
Angiotensin Receptor
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Smiles
O=C(C(C=CC=C1)=C1C(O[Na])=O)NC(C=C2)=CC=C2CN3C(CC(OC)=O)=C(N=C3CCCC)Cl
Molecular Formula
C25H25ClN3NaO5
Molecular Weight
505.93
References & Citations
[1]Wong PC, et al. Nonpeptide angiotensin II receptor antagonists. IV. EXP6155 and EXP6803. Hypertension. 1989 May;13 (5) :489-97.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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