BB-83698
BB-83698 is a peptide deformylase (PDF) inhibitor. BB-83698 exhibits potent in vitro activity against Streptococcus pneumoniae, with a minimum inhibitory concentration (MIC) range of 0.06-0.25μg/mL. BB-83698 elevates the survival rate of mice regardless of whether the infecting strain carries resistance mechanisms. BB-83698 can be used for the study of the treatment of diseases related to drug-resistant Streptococcus pneumoniae infections[1].
Product Specifications
CAS Number
[325795-25-3]
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C([C@H](C(C)(C)C)NC([C@@H](CN(O)C=O)CC1CCCC1)=O)N2CCN(CC2)CC3=CC=C4C(OCO4)=C3
Molecular Formula
C28H42N4O6
Molecular Weight
530.66
References & Citations
[1]Azoulay-Dupuis E, et al. Efficacy of BB-83698, a novel peptide deformylase inhibitor, in a mouse model of pneumococcal pneumonia. Antimicrob Agents Chemother. 2004 Jan;48 (1) :80-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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