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L694247 (TFA)

L694247 (TFA) is a selective 5-HT1D agonist with pIC50 values of 10.03, 8.64, 6.42, and 5.66 for 5-HT1D, 5-HT1A, 5-HT1C, and 5-HT1E receptors, respectively[1].

Product Specifications

UNSPSC

12352005

Target

5-HT Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Inflammation/Immunology; Neurological Disease

Smiles

NCCC1=CNC2=C1C=C(C3=NC(CC4=CC=C(C=C4)NS(C)(=O)=O)=NO3)C=C2.FC(F)(C(O)=O)F

Molecular Formula

C22H22F3N5O5S

Molecular Weight

525.50

References & Citations

[1]Beer MS, et al. L-694,247: a potent 5-HT1D receptor agonist. Br J Pharmacol. 1993;110 (3) :1196-1200.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Isoform

5-HT1 Receptor

Curated Selection

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