BAPTA (Standard)

BAPTA (Standard) is the analytical standard of BAPTA. This product is intended for research and analytical applications. BAPTA is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA can also inhibit phospholipase C activity independently of their role as Ca2+ chelators[1][2].

Product Specifications

CAS Number

[85233-19-8]

UNSPSC

12352005

Target

Phospholipase; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Others

Smiles

O=C(O)CN(C1=CC=CC=C1OCCOC2=CC=CC=C2N(CC(O)=O)CC(O)=O)CC(O)=O

Molecular Formula

C22H24N2O10

Molecular Weight

476.43

References & Citations

[1]R Y Tsien, et al. New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures. Biochemistry. 1980 May 27;19 (11) :2396-404. |[2]Roger C Hardie, et al. Inhibition of phospholipase C activity in Drosophila photoreceptors by 1,2-bis (2-aminophenoxy) ethane N, N, N', N'-tetraacetic acid (BAPTA) and di-bromo BAPTA. Cell Calcium. 2005 Dec;38 (6) :547-56. |[3]M B Collatz, et al. Intracellular calcium chelator BAPTA protects cells against toxic calcium overload but also alters physiological calcium responses. Cell Calcium