Septide
Septide ((Pyr6, Pro9) -Substance P) is a potent NK1 receptor agonist with a Kd value of 0.55 nM[1].
Product Specifications
CAS Number
[79775-19-2]
Product Name Alternative
(Pyr6, Pro9) -Substance P
UNSPSC
12352209
Target
Neurokinin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/septide.html
Purity
98.97
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@H]1NC(CC1)=O)N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC3=CC=CC=C3)C(N4[C@@H](CCC4)C(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCSC)=O)=O)=O)=O
Molecular Formula
C39H53N7O7S
Molecular Weight
763.95
References & Citations
[1]Hastrup H, Schwartz TW. Septide and neurokinin A are high-affinity ligands on the NK-1 receptor: evidence from homologous versus heterologous binding analysis. FEBS Lett. 1996 Dec 16;399 (3) :264-6.|[2]Pradier L, Mayaux JF, et al. Septide: an agonist for the NK1 receptor acting at a site distinct from substance P. Mol Pharmacol. 1994 Feb;45 (2) :287-93.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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