LRRC15 Protein, Human, Recombinant (His & Avi)

The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA) -mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. LRRC15 Protein, Human, Recombinant (His & Avi) is expressed in CHO mammalian cells with C-His-Avi tag. The predicted molecular weight is 60.7 kDa and the accession number is Q8TF66-1.