Sigvotatug
Product Specifications
CAS Number
2764774-90-3
Target
Antibody-Drug Conjugates (ADCs) |||Integrin
Related Pathways
Antibody-drug Conjugate/ADC Related|||Cytoskeletal Signaling
Purity
0.987
Bioactivity
Sigvotatug Vedotin is an antibody-drug conjugate (ADC) designed to selectively target integrin ?v?6-positive tumor cells through an engineered antibody with high specificity. Sigvotatug Vedotin employs a protease-cleavable linker that delivers the cytotoxic payload monomethyl auristatin E (MMAE), a microtubule inhibitor, directly into tumor cells. Upon internalization, MMAE disrupts microtubule organization, inhibits proper cell division, and ultimately results in tumor cell death, providing a targeted strategy in oncology research.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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