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ABX-MA1

Product Specifications

CAS Number

561063-60-3

Target

MMP

Related Pathways

Proteases/Proteasome

Bioactivity

ABX-MA1 is a humanized IgG2 monoclonal antibody inhibitor targeting MCAM/MUC18. It significantly reduces homotypic aggregation and heterotypic adhesion with HUVEC, as well as the formation of experimental lung metastasis. In A375SM/WM2664 xenograft mouse models, ABX-MA1 effectively suppresses tumor growth, angiogenesis, and MMP-2 expression, indicating potential for melanoma research.

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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