ZJCK-6-46
Product Specifications
Target
DYRK
Related Pathways
Tyrosine Kinase/Adaptors|||Cell Cycle/Checkpoint
Bioactivity
ZJCK-6-46 (32) is a potential orally active DYRK1A inhibitor (IC50= 0.68 nM) with favorable CNC permeability. It downregulates tau phosphorylation and improves cognitive impairments by significantly reducing the expression of phosphorylated tau proteins and neuronal loss.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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