Casdatifan

Product Specifications

CAS Number

2709069-30-5

Target

HIF/HIF Prolyl-Hydroxylase

Related Pathways

Metabolism|||Chromatin/Epigenetic

Bioactivity

Casdaitifan (AB521) is an orally active hypoxia inducible factor 2 alpha (HIF-2 alpha) inhibitor. Casdaitifan exhibits significant anti-tumor effects in the clear cell renal cell carcinoma (ccRCC) model.

Smiles

C(#N)C1=C2[C@H](C[C@H](F)[C@H](F)C2=CC(F)=C1)C3=C4C(=C(S(C)(=O)=O)C=C3)[C@H](O)[C@H](F)C4

Molecular Formula

C21H17F4NO3S

Molecular Weight

439.42

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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