KIF18A-IN-10

Product Specifications

CAS Number

3034542-28-1

Target

Microtubule Associated|||Kinesin

Related Pathways

Cytoskeletal Signaling

Bioactivity

KIF18A-IN-10 (Compound 24) is a potent inhibitor of KIF18A with an IC50 value of 3.8 nM. It exhibits anticancer activity with IC50 values below 100 nM in OVCAR3 and MDA-MB-157 cells.

Smiles

O=C(NC1=NC2=C(C=NN2C3CC(F)(F)C3)C=C1)C4=CC=C(C=C4N5CCC6(CC5)CC6)NS(=O)(=O)CCO

Molecular Formula

C26H30F2N6O4S

Molecular Weight

560.62

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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