PSMA-Val-Cit-PAB-Azide

Product Specifications

CAS Number

2374814-84-1

Target

Drug-Linker Conjugates for ADC|||PSMA

Related Pathways

Immunology/Inflammation|||Antibody-drug Conjugate/ADC Related

Bioactivity

PSMA-Val-Cit-PAB-Azide, a drug-linker conjugate for Antibody-Drug Conjugates (ADCs), incorporates a cleavable linker (Val-Cit-PAB) and a novel small-molecule conjugate targeting PSMA. This compound features an Azide group, enabling it to participate in the copper-catalyzed azide-alkyne cycloaddition reaction (CuAAC) with Alkyne-group-containing molecules [1].

Smiles

[C@H](CC1=CC=CC=C1)(C(N[C@@H](CC2=CC=C(O)C=C2)C(NCCCN=[N+]=[N-])=O)=O)NC(CCC(NCCCCCC(N(CC3=CC(Cl)=CC=C3)CCCC[C@H](NC(N[C@@H](CCC(O)=O)C(O)=O)=O)C(O)=O)=O)=O)=O