Sigma-2 Radioligand 1
Product Specifications
CAS Number
2860554-32-9
Target
Sigma receptor
Related Pathways
GPCR/G Protein
Bioactivity
Sigma-2 Radioligand 1 (compound 1) serves as a selective Sigma-2 ligand, demonstrating favorable biodistribution in mice and robust in vivo activity in rats. The [18F] modified version of Sigma-2 Radioligand 1 enhances the visualization of tumors in micro-PET/CT imaging by providing high tumor uptake and an impressive tumor-to-background ratio. Additionally, experiments confirm that this compound binds with high specificity to U87MG glioma xenografts [1].
Smiles
C(CCCN1CC=2C(CC1)=CC(OC)=C(OC)C2)N3C=4C(N(CCF)C3=O)=CC=CC4
Molecular Formula
C24H30FN3O3
Molecular Weight
427.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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