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POP-3MB

Product Specifications

CAS Number

1144114-27-1

Target

ERK|||Transferase

Related Pathways

MAPK|||Metabolism

Bioactivity

POP-3MB (compound 1b) acts as an inhibitor of ICMT, displaying an IC50 value of 2.5 ?M. This compound not only alters the subcellular localization of K-Ras but also impedes Ras activation and inhibits Erk phosphorylation [1].

Smiles

O(C1=C(C(N[C@@H](CSCC=C(CCC2=CC=C(C=C2)C3=CC=CC=C3)CC=C(C)C)C(O)=O)=O)C=CC=C1)C4=CC=CC=C4

Molecular Formula

C38H39NO4S

Molecular Weight

605.79

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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