LRRK2-IN-12
Product Specifications
Target
LRRK2
Related Pathways
Autophagy
Bioactivity
LRRK2-IN-12 (compound 1) is a potent inhibitor of LRRK2 (G20195) with an IC 50 of 0.45 nM, LRRK2 WT with an IC 50 of 1.1 nM, and LRRK2 WT ADP-Glo with an IC 50 of 0.46 nM. This compound is utilized in research related to Alzheimer's Disease [1].
Smiles
ClC=1C2=C3N(N1)CCCOC=4C(N=C(N3)N=C2)=C(C)N(N4)C5=C(OC)N=CC=C5
Molecular Formula
C18H17ClN8O2
Molecular Weight
412.83
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/212216107396759601/T86823
CAS Number
3032733-05-1
Available Sizes
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