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LRRK2-IN-12

Product Specifications

Target

LRRK2

Related Pathways

Autophagy

Bioactivity

LRRK2-IN-12 (compound 1) is a potent inhibitor of LRRK2 (G20195) with an IC 50 of 0.45 nM, LRRK2 WT with an IC 50 of 1.1 nM, and LRRK2 WT ADP-Glo with an IC 50 of 0.46 nM. This compound is utilized in research related to Alzheimer's Disease [1].

Smiles

ClC=1C2=C3N(N1)CCCOC=4C(N=C(N3)N=C2)=C(C)N(N4)C5=C(OC)N=CC=C5

Molecular Formula

C18H17ClN8O2

Molecular Weight

412.83

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/212216107396759601/T86823

CAS Number

3032733-05-1

Available Sizes

Curated Selection

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