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JAK/HDAC-IN-3

Product Specifications

CAS Number

3029138-70-0

Target

HDAC|||JAK

Related Pathways

DNA Damage/DNA Repair|||Stem Cells|||Angiogenesis|||Chromatin/Epigenetic|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

Bioactivity

JAK/HDAC-IN-3 (13a), a dual inhibitor of JAK and HDAC, exhibits IC50 values of 25.36 nM for JAK2, 0.2 ?M for HDAC, and 0.43 ?M for HDAC1, respectively [1].

Smiles

N(C1=NC(NC2=CC(F)=C(OCCCCCCC(NO)=O)C=C2)=NC=C1C)C3=CC(S(NC(C)(C)C)(=O)=O)=CC=C3

Molecular Formula

C28H37FN6O5S

Molecular Weight

588.69

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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