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AQIM-I

Product Specifications

CAS Number

2247881-73-6

Target

Survivin

Related Pathways

Apoptosis

Bioactivity

AQIM-I is a survivin inhibitor that reduces survivin expression and colony formation. It promotes reactive oxygen species (ROS) production, apoptosis, cell cycle arrest, DNA damage, and autophagy. Moreover, AQIM-I effectively inhibits nonsmall cell lung cancer cells A549, with an IC 50 value of 9 nM [1].

Smiles

[I-].O=C1C2=CC=3C=CC=CC3C=C2C(=O)C4=C1N(C=[N+]4C)C

Molecular Formula

C17H13IN2O2

Molecular Weight

404.2

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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