TM11
Product Specifications
UNSPSC Description
TM11, a Tanshinone mimic, is a potent HuR inhibitor that can inhibit HuR-RNA complex formation. TM11 reduces LPS-induced inflammatory response in murine macrophages[1].
Target Antigen
HuR
Type
Reference compound
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tm11.html
Smiles
O=S(C1=CC=CC=C1)(C2C(C=CC(C3=O)=O)=C3C(C4=CC=CO4)=C2)=O
Molecular Weight
352.36
References & Citations
[1]Facen E, et, al. Novel, soluble 3-heteroaryl-substituted tanshinone mimics attenuate the inflammatory response in murine macrophages. Sci Rep. 2024 Oct 18;14(1):24501.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168539/TM11-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168539/
Clinical Information
No Development Reported
Curated Selection
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