GPR34 receptor antagonist 3
Product Specifications
Target
Orphan Receptor|||Others|||ERK
Related Pathways
Others|||GPCR/G Protein|||MAPK
Bioactivity
Compound 5e, a GPR34 receptor antagonist, exhibits selective inhibition of lysophosphatidylserine-induced ERK1/2 phosphorylation in a dose-dependent manner, demonstrating an IC50 value of 0.680 ?M without significant cytotoxicity. Additionally, it displays antisensory activity in a mouse neuropathic pain model [1].
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/132882306451898405/T82264
Available Sizes
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