Shishijimicin B

Shishijimicin B, an enediyne class compound, exhibits extremely potent cytotoxicity, with IC50 values ranging from 2.0-3.3 nM. This compound has been noted for its antitumor activity, making it valuable for cancer research [1]. Additionally, Shishijimicin B serves as a click chemistry reagent due to its Alkyne group, allowing for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Azide-containing molecules.