Guvacine hydrobromide
Product Specifications
CAS Number
6027-92-5
Target
GABA Receptor
Related Pathways
Neuroscience|||Membrane transporter/Ion channel
Bioactivity
Guvacine hydrobromide, an alkaloid derived from the Areca catechu nut, serves as a potent inhibitor of GABA (GABA uptakp) uptake. It effectively inhibits rat GABA transporter isoforms GAT-1, GAT-2, and GAT-3, with respective IC50 values of 39 ?M, 58 ?M, and 378 ?M [1].
Smiles
Br.O=C(O)C1=CCCNC1
Molecular Formula
C6H10BrNO2
Molecular Weight
208.05
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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