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PI3K?-IN-14

Product Specifications

Target

PI3K

Related Pathways

PI3K/Akt/mTOR signaling

Bioactivity

PI3K?-IN-14 (Compound (S) -29), a selective PI3K? inhibitor with an IC50 of 0.8 nM and a Kd of 84.8 nM, targets the ATP-binding site within the kinase domain of PI3K?, exhibiting anti-inflammatory properties by impeding the PI3K/AKT pathway and alleviating acute lung injury (ALI) [1].

Molecular Formula

C26H20ClFN8O

Molecular Weight

514.94

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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