PI3K?-IN-14
Product Specifications
Target
PI3K
Related Pathways
PI3K/Akt/mTOR signaling
Bioactivity
PI3K?-IN-14 (Compound (S) -29), a selective PI3K? inhibitor with an IC50 of 0.8 nM and a Kd of 84.8 nM, targets the ATP-binding site within the kinase domain of PI3K?, exhibiting anti-inflammatory properties by impeding the PI3K/AKT pathway and alleviating acute lung injury (ALI) [1].
Molecular Formula
C26H20ClFN8O
Molecular Weight
514.94
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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