Sirt1/2-IN-3
Product Specifications
CAS Number
301313-42-8
Target
Sirtuin|||Apoptosis
Related Pathways
Apoptosis|||Chromatin/Epigenetic|||DNA Damage/DNA Repair
Bioactivity
Sirt1/2-IN-3 (compound PS9) serves as a dual inhibitor of SIRT1/2, exhibiting IC50 values of 1.4 ?M (SIRT1) and 2.0 ?M (SIRT2), respectively. This compound effectively inhibits p53 deacetylation while simultaneously elevating p53 and ?-tubulin acetylation levels. Additionally, Sirt1/2-IN-3 promotes apoptosis and exhibits antiproliferative effects on human leukemia cell lines [1].
Smiles
COC1=CC=C(C=C1)S(=O)(=O)NC1=C2C=CC=CC2=C(O)C(Cl)=C1
Molecular Formula
C17H14ClNO4S
Molecular Weight
363.82
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Monoclonal HPV16 Antibody (716-325) [DyLight 755]](https://cdn.genprice.uk/genprice/uk/genprice3.webp)
MBS1293989-01 0.02 mg (E-Coli)
Recombinant Escherichia coli UPF0758 protein ykfG (ykfG)
Ask
View Details