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PARP1-IN-15

Product Specifications

Target

Apoptosis|||PARP

Related Pathways

Apoptosis|||DNA Damage/DNA Repair|||Chromatin/Epigenetic

Bioactivity

PARP1-IN-15 (Compound 6) is a PARP1 inhibitor that also inhibits tankyrase (TNKS) and promotes DNA double-strand breaks, leading to tumor cell apoptosis. It exhibits anti-cancer activity in triple-negative breast cancer (TNBC) cells and patient-derived organoids, making it useful for TNBC research, including cases with or without BRCA1 mutations [1].

Molecular Formula

C16H12N2O2

Molecular Weight

264.28

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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