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Anticancer agent 136

Product Specifications

Target

Apoptosis

Related Pathways

Apoptosis

Bioactivity

Anticancer agent 136 (compound 22), a C17-triazole analogue of Geldanamycin (GDM), exhibits an IC50 value of 3.38 ?M against human dermal fibroblasts (HDF) and binds to Heat shock protein 90 (Hsp90) with a dissociation constant (Kd) of 3.86 ?M, demonstrating its apoptosis-inducing capabilities [1].

Molecular Formula

C40H50N6O8

Molecular Weight

742.86

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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