Demethyleneberberine chloride
Product Specifications
CAS Number
16705-03-6
Target
AMPK|||NF-?B
Related Pathways
NF-?B|||PI3K/Akt/mTOR signaling|||Chromatin/Epigenetic
Bioactivity
Demethyleneberberine chloride, a natural mitochondria-targeted antioxidant, mitigates colitis in mice and suppresses inflammatory responses by blocking the NF-?B pathway and modulating the equilibrium of Th cells. It is also recognized as an AMPK activator for investigating non-alcoholic fatty liver disease (NAFLD) [1] [2] [3].
Smiles
[Cl-].OC=1C=C2C=3C=C4C=CC(OC)=C(OC)C4=C[N+]3CCC2=CC1O
Molecular Formula
C19H18ClNO4
Molecular Weight
359.8
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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