Pomalidomide-5-C10-NH2 hydrochloride

Product Specifications

CAS Number

2863635-00-9

Target

Others|||E3 Ligase Ligand-Linker Conjugate

Related Pathways

Others|||PROTAC

Bioactivity

Pomalidomide-5-C10-NH2 hydrochloride, a Pomalidomide-derived cereblon (CRBN) ligand, facilitates the recruitment of CRBN protein. This compound can be tethered to a protein ligand via a linker to construct a PROTAC [1].

Smiles

Cl.O=C1NC(=O)C(N2C(=O)C3=CC=C(C=C3C2=O)NCCCCCCCCCCN)CC1

Molecular Formula

C23H33ClN4O4

Molecular Weight

464.99

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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