MSU-42011
Product Specifications
CAS Number
2456434-36-7
Target
NOS|||Retinoid Receptor|||Ras|||Lipid|||Kras|||PERK|||NO Synthase
Related Pathways
Apoptosis|||Metabolism|||Immunology/Inflammation|||MAPK
Purity
0.996
Bioactivity
MSU-42011 is an orally active retinoid X receptor-like (RXR) agonist. It potently inhibits the expression of iNOS, low SREBP-induced and activated RXR, and p-ERK at the protein level. MSU-42011 has demonstrated antitumor activity in a [kras]-driven mouse model of lung cancer and is effective for the treatment of preclinical [kras]-driven lung cancer with immunomodulatory activity.
Smiles
N(CC(C)C)(C1=CC(C(C)(C)C)=CC(C(C)(C)C)=C1)C2=CC=C(C(O)=O)C=N2
Molecular Formula
C24H34N2O2
Molecular Weight
382.54
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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