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Ac-YVAD-CHO acetate

Product Specifications

Target

Others|||Interleukin|||Apoptosis|||Caspase

Related Pathways

Others|||Proteases/Proteasome|||Apoptosis|||Immunology/Inflammation

Bioactivity

Ac-YVAD-CHO (L-709049) acetate is a potent, reversible, and specific tetrapeptide interleukin-1? converting enzyme (ICE) inhibitor, also demonstrating specificity for caspase-1. It exhibits K_i values of 3.0 nM in mice and 0.76 nM in humans, underscoring its efficacy. Additionally, Ac-YVAD-CHO acetate inhibits the production of mature IL-1?, highlighting its therapeutic potential [1] [2] [3].

Molecular Formula

C25H36N4O10

Molecular Weight

552.57

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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