DOCK2-IN-1
Product Specifications
CAS Number
4590-86-7
Target
Others
Related Pathways
Others
Bioactivity
DOCK2-IN-1, an analogue of CPYPP, effectively inhibits DOCK2 (IC50 = 19.1 ?M) by reversibly binding to its DHR-2 domain, thereby hindering its catalytic function. This compound obstructs the activation of Rac in lymphocytes, triggered either by chemokine or antigen receptors. Consequently, DOCK2-IN-1 markedly reduces chemotactic responses and T cell activation [1].
Smiles
O=C1N(NC(=O)C1=CC2=C(Cl)C=CC=C2)C3=CC=CC=C3
Molecular Formula
C16H11ClN2O2
Molecular Weight
298.72
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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