EGFR/HER2-IN-9

Product Specifications

CAS Number

1637253-79-2

Target

EGFR|||Others

Related Pathways

Tyrosine Kinase/Adaptors|||Angiogenesis|||JAK/STAT signaling|||Others

Bioactivity

EGFR/HER2-IN-9, a compound inhibiting both EGFR and HER2, demonstrates potency with IC50 values of 3.2 nM for EGFR, 14 nM for HER2, and 8.3 nM against the EGFR T790M mutation.

Smiles

N(C=1C2=C(C=C(OC)C(NC(/C=C/CN3C[C@@]4([C@](C3)(OCCO4)[H])[H])=O)=C2)N=CN1)C5=CC(Cl)=C(F)C=C5

Molecular Formula

C25H25ClFN5O4

Molecular Weight

513.95

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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