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AM-9635

Product Specifications

CAS Number

1338483-10-5

Target

Others|||PI3K|||Akt

Related Pathways

Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling|||Others

Bioactivity

AM-9635 is a potent and selective PI3K? inhibitor. AM-9635 showes good cellular potency (in vitro pAKT IC50 = 4.2 nM) . AM-96352 inhibits KLH-specific IgG and IgM in a dosedependent manner AM-9635 is well tolerated at all doses and exhibits significantly reduced IgG and IgM specific antibodies . PI3K? and PI3K? are ubiquitously expressed and play a role in cell growth, division, and survival.

Smiles

[C@H](NC=1C(C#N)=C(N)N=CN1)(C)C=2N(C=3C(N2)=CC=C(F)C3)C=4C=C(F)C=NC4

Molecular Formula

C19H14F2N8

Molecular Weight

392.36

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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