NZ-28
Product Specifications
CAS Number
75041-32-6
Target
Others
Related Pathways
Others
Bioactivity
NZ28, also known as NSC134754, is potent HSF1 inhibitor, which induced inhibition of HSF1, SP1 and NF-?B triggers the loss of the natural killer cell-activating ligands MICA/B on human tumor cells. Heat-shock transcription factor HSF1 has a critical role in human epidermal growth factor receptor-2-induced cellular transformation and tumorigenesis.
Smiles
C(C=1C[C@]2(C=3C(=CC(OC)=C(OC)C3)CCN2CC1CC)[H])[C@@H]4C=5C(CCN4)=CC=CC5
Molecular Formula
C27H34N2O2
Molecular Weight
418.57
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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