NVP-QBE170
Product Specifications
CAS Number
1080018-61-6
Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
NVP-QBE170 is a selective epithelial sodium channel (ENaC) inhibitor with an IC50 of 57.5 nM. It effectively suppresses ENaC function in human bronchial epithelial cells (HBEC), with a prolonged duration of action. NVP-QBE170 significantly decreases ENaC activity in guinea pig airway models and can be utilized for hyperkalemia research.
Smiles
O=C(NC(=N)NC1CCN(C(=O)C2=CC=C(C=C2)C(=O)N3CCC(NC(=N)NC(=O)C4=NC(Cl)=C(N=C4N)N)CC3)CC1)C5=NC(Cl)=C(N=C5N)N
Molecular Formula
C30H36Cl2N16O4
Molecular Weight
755.62
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6143890-01 0.1 mL
RABGGTB (Geranylgeranyl Transferase Type-2 Subunit beta, Geranylgeranyl Transferase Type II Subunit beta, GGTase-II-beta, Rab Geranyl-geranyltransferase Subunit beta, Rab GG Transferase beta, Rab GGTase beta, Rab Geranylgeranyltransferase Subunit beta, Ty
Ask
View Details 
MBS6143890-02 5x 0.1 mL
RABGGTB (Geranylgeranyl Transferase Type-2 Subunit beta, Geranylgeranyl Transferase Type II Subunit beta, GGTase-II-beta, Rab Geranyl-geranyltransferase Subunit beta, Rab GG Transferase beta, Rab GGTase beta, Rab Geranylgeranyltransferase Subunit beta, Ty
Ask
View Details 