KRAS IN-44
Product Specifications
Target
PDE|||PI3K|||Akt|||Apoptosis|||Ras|||mTOR
Related Pathways
Cytoskeletal Signaling|||MAPK|||PI3K/Akt/mTOR signaling|||Metabolism|||Apoptosis
Bioactivity
KRAS IN-44 (Compound S2C2M2) is a PDE6D degrader. It inhibits PDE6D-dependent KRAS transport and downstream signaling pathways. Additionally, KRAS IN-44 downregulates EGF-induced phosphorylation of PI3K, AKT, and mTOR. It promotes apoptosis and exhibits antitumor activity against hepatoblastoma.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1477304-01 0.02 mg (E-Coli)
Recombinant Pyrococcus furiosus Hydroxyethylthiazole kinase (thiM)
Ask
View Details MBS1477304-02 0.02 mg (Yeast)
Recombinant Pyrococcus furiosus Hydroxyethylthiazole kinase (thiM)
Ask
View Details 
MBS1477304-03 0.1 mg (E-Coli)
Recombinant Pyrococcus furiosus Hydroxyethylthiazole kinase (thiM)
Ask
View Details MBS1477304-04 0.1 mg (Yeast)
Recombinant Pyrococcus furiosus Hydroxyethylthiazole kinase (thiM)
Ask
View Details