VEGFR-2/STAT-3-IN-1
Product Specifications
Target
VEGFR|||STAT
Related Pathways
Tyrosine Kinase/Adaptors|||Stem Cells|||JAK/STAT signaling|||Angiogenesis
Bioactivity
VEGFR-2/STAT-3-IN-1 (Compound 9f) is a dual inhibitor targeting VEGFR-2 with an IC50 of 26.3 nM and STAT-3 with an IC50 of 5.63 nM. It suppresses the proliferation of cancer cells PANC1 and PC3, with IC50 values of 0.14 and 0.10 µM, respectively, and induces apoptosis in PC3 cells.
Molecular Formula
C26H20N6O4
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/372420802911404247/T210364
Available Sizes
Curated Selection
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