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VEGFR-2/STAT-3-IN-1

Product Specifications

Target

VEGFR|||STAT

Related Pathways

Tyrosine Kinase/Adaptors|||Stem Cells|||JAK/STAT signaling|||Angiogenesis

Bioactivity

VEGFR-2/STAT-3-IN-1 (Compound 9f) is a dual inhibitor targeting VEGFR-2 with an IC50 of 26.3 nM and STAT-3 with an IC50 of 5.63 nM. It suppresses the proliferation of cancer cells PANC1 and PC3, with IC50 values of 0.14 and 0.10 µM, respectively, and induces apoptosis in PC3 cells.

Molecular Formula

C26H20N6O4

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/372420802911404247/T210364

Available Sizes

Curated Selection

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