Anti-MRSA agent 14

Product Specifications

CAS Number

3050586-22-3

Target

Antibacterial

Related Pathways

Microbiology/Virology

Bioactivity

Anti-MRSA agent 14 (Compound C17) exhibits antibacterial activity against MRSA and in a MRSA-infected mouse skin model. It demonstrates greater potential against MRSA compared to Norfloxacin. Anti-MRSA agent 14 disrupts cell membranes and inhibits metabolism. Its antibacterial MIC values against S. aureus ATCC 6538, S. aureus ATCC 29213, S. epidermidis ATCC 12228, and MRSA are 1, 2, 2, and 1 ?M, respectively.

Smiles

C(NS(=O)(=O)C1=CC=C(Cl)C=C1)(=O)[C@]23[C@](C=4[C@@](C)(CC2)[C@@]5(C)[C@](CC4)([C@]6(C)[C@@](CC5)(C(C)(C)C7=C(C6)C=8C(N7)=C(C(O)=O)C=CC8)[H])[H])(CC(C)(C)CC3)[H]