Antiparasitic agent-22

Product Specifications

Target

Parasite

Related Pathways

Microbiology/Virology

Bioactivity

Antiparasitic agent-22 (Compound 24) is a broad-spectrum antiparasitic compound that inhibits the procyclic form of T. brucei, L. infantum, and L. tropica with IC50 values of 2.41, 5.95, and 8.98 ?M, respectively, and the amastigote form of L. infantum with an IC50 of 8.18 ?M. It also shows inhibitory activity against the P. falciparum W2 strain with an IC50 of 0.155 ?M. Additionally, Antiparasitic agent-22 exhibits low cytotoxicity in THP1 cells, with a CC50 of 64.16 ?M.