PROTAC SOS1 degrader-6

3032282-51-9

Ras|||PROTACs

MAPK|||PROTAC

PROTACSOS1 degrader-6 (compound 23) is an effective degrader of SOS1 PROTACs and works synergistically with KRASG12C inhibitors.

N([C@H](C)C1=CC(C(F)(F)F)=CC(N)=C1)C=2C3=C(C=C(OC)C(OCCCCC(N[C@H](C(=O)N4[C@H](C(NCC5=CC=C(C=C5)C=6SC=NC6C)=O)C[C@@H](O)C4)C(C)(C)C)=O)=C3)N=C(C)N2

C46H55F3N8O6S

905.04

Cool pack

-20°C