TEAD1/3/4-IN-1
Product Specifications
CAS Number
2762619-63-4
Target
YAP
Related Pathways
Stem Cells
Purity
0.9925
Bioactivity
TEAD1/3/4-IN-1 (compound 1) is an inhibitor of TEAD1/3/4 that suppresses YAP/TAZ-TEAD interactions. It exhibits antitumour activity against NF2-deficient NCI-H226 cells and may be employed in studies of cancer and diseases mediated by Hippo pathway abnormalities.
Smiles
O=C(C(F)=C)N1CC(N2C(=O)N(C3=CC=C(C=C3)C(F)(F)F)C4=NC=CN=C42)C1
Molecular Formula
C18H13F4N5O2
Molecular Weight
407.32
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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