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CLK2/3-IN-1

Product Specifications

Target

CDK

Related Pathways

Cell Cycle/Checkpoint

Bioactivity

CLK2/3-IN-1 (Compound 7c) is an orally active inhibitor of CLK2/3, with EC50 values of 5.07 nM and 30.03 nM, respectively. Its inhibitory action is facilitated by hydrogen bonding with Lys193 and Lys186 residues of CLK2/3. This compound effectively inhibits the proliferation of SW480 tumor cells with an IC50 of 163 nM and is applicable for research into CLK-related cancer diseases.

Molecular Formula

C24H25N7O

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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